Bluetongue virus

Bluetongue virus

MATERIAL SAFETY DATA SHEET - INFECTIOUS SUBSTANCES

SECTION I - INFECTIOUS AGENT

NAME: Bluetongue virus

SYNONYM OR CROSS REFERENCE: None

CHARACTERISTICS: Double capsid shell, naked, icosahedral virion; 60-80 nm diameter; segmented, linear, double-stranded RNA genome; Reoviridae; genus Orbivirus

SECTION II - HEALTH HAZARD

PATHOGENICITY: A non contagious, insect-transmitted, viral disease of sheep, cattle, goats, and wild ruminants

EPIDEMIOLOGY: The disease occurs widely on the African continent and to a lesser extent in North America, Asia, and Europe. In Canada, seroreactors are restricted to the Okanagan Valley

HOST RANGE: Sheep, cattle, goats and wild ruminants

INFECTIOUS DOSE: Not known

MODE OF TRANSMISSION: Non contagious; biologically transmitted by biting insects of the genus Culicoides

INCUBATION PERIOD: The usual incubation period in sheep is 5-10 days

COMMUNICABILITY: Non contagious

SECTION III - DISSEMINATION

RESERVOIR: Cattle and some wild ruminant species may act as reservoirs for sheep

ZOONOSIS: None

VECTORS: Biting insects of the genus Culicoides

SECTION IV - VIABILITY

DRUG SUSCEPTIBILITY: Not applicable

SUSCEPTIBILITY TO DISINFECTANTS: Susceptible to 95% ethanol, 2% formalin, 5% lysol, 2% sodium hypochlorite but requires prolonged exposure

PHYSICAL INACTIVATION: Stable at acidic pH (3.0-3.5), sensitive to heating above 50°C

SURVIVAL OUTSIDE HOST: Survives for months at 4°C and 20°C

SECTION V - MEDICAL

SURVEILLANCE: Not applicable

FIRST AID/TREATMENT: Not applicable

IMMUNIZATION: Not applicable

PROPHYLAXIS: Not applicable

SECTION VI - LABORATORY HAZARDS

LABORATORY-ACQUIRED INFECTIONS: None

SOURCES/SPECIMENS: Whole blood

PRIMARY HAZARDS: None

SPECIAL HAZARDS: None

SECTION VII - RECOMMENDED PRECAUTIONS

CONTAINMENT REQUIREMENTS: Bluetongue virus is considered to be not indigenous to Canada. Agriculture Canada will establish conditions under which the virus is used and maintained

PROTECTIVE CLOTHING: Solid front gown

OTHER PRECAUTIONS: None

SECTION VIII - HANDLING INFORMATION

SPILLS: Cover spill with absorbent paper towel and apply 2% sodium hypochlorite starting at the perimeter and working towards the centre; wait 30 min before clean up

DISPOSAL: Decontaminate all wastes before disposal; steam sterilization, chemical disinfection, incineration

STORAGE: Sealed containers, appropriately labelled

SECTION IX - MISCELLANEOUS INFORMATION

Date prepared: November 1999

Prepared by: Office of Laboratory Security, PHAC

Although the information, opinions and recommendations contained in this Material Safety Data Sheet are compiled from sources believed to be reliable, we accept no responsibility for the accuracy, sufficiency, or reliability or for any loss or injury resulting from the use of the information. Newly discovered hazards are frequent and this information may not be completely up to date.

Copyright © Health Canada, 2001

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